Associate VP - Health Economics and Outcomes Research (HEOR) - Global CMH

Company: Eli Lilly and Company
Location: Indianapolis
Posted on: February 1, 2026

Job Description:

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world. Position Overview We are seeking an exceptional leader to lead our Real-World Evidence (RWE) function for Lilly Cardiometabolic Health (CMH). This individual will report to the President of Lilly CMH and sit on the CMH Leadership Team, with responsibility for shaping our RWE strategy and portfolio of projects, managing a team of RWE scientists, delivering strong evidence to support registration plans, new uses and NILEX, and demonstrate the value of our medicines. This includes our portfolio of groundbreaking therapies across obesity, diabetes, cardiovascular disease, and related metabolic conditions. Key Responsibilities Strategic Leadership & Portfolio Management Provide strategic oversight of the cardiometabolic RWE portfolio, aligning evidence generation with business objectives Work collaboratively with cross-functional partners including Medical Affairs, Commercial, Patient/Regulatory Affairs (PRA), and Development teams to identify evidence gaps and establish project priorities Oversee the design, execution, and delivery of a diverse portfolio of RWE studies across cardiovascular disease, diabetes, obesity, and metabolic disorders Ensure all RWE projects are delivered on time, within budget, and to the highest scientific standards Execute publication and communication strategies that maximize scientific impact and visibility of RWE findings Team Leadership & Development Recruit, develop, and manage a high-performing team of RWE scientists with diverse expertise in epidemiology, biostatistics, health economics, and outcomes research Foster a culture of scientific excellence, innovation, and collaboration within the RWE team Provide mentorship and career development opportunities for team members Build team capabilities in emerging RWE methodologies and data sources External Partnerships & Collaboration Forge strategic partnerships with leading academic institutions, research organizations, and healthcare data companies to access novel data sets and advanced analytic capabilities Identify and evaluate external collaborators with unique data assets (e.g., EHR systems, claims databases, registries, wearable device data) Negotiate and manage collaboration agreements that advance Lilly's RWE objectives Represent Lilly in external scientific forums and maintain relationships with key opinion leaders in real-world evidence Evidence Generation for Business Impact Generate real-world evidence to support regulatory submissions and post-approval requirements, working closely with development teams Identify new therapeutic uses and potential New Indication for a Licensed Product (NILEX) opportunities through analysis of real-world data patterns Demonstrate the clinical and economic value of Lilly's cardiometabolic medicines through rigorous comparative effectiveness research, health outcomes studies, and health economic analyses Translate RWE findings into actionable insights for commercial strategy and medical affairs initiatives Scientific Excellence & Thought Leadership Ensure all RWE studies adhere to best practices in study design, analysis, and reporting (ISPOR guidelines, STROBE, etc.) Develop and implement innovative methodologies for causal inference, comparative effectiveness, and patient outcomes assessment Drive scientific disclosure through high-impact publications, presentations at major conferences, and engagement with the scientific community Stay current with evolving regulatory guidance on RWE and ensure compliance across all studies Qualifications Required PhD, PharmD, MD, or equivalent advanced degree in epidemiology, health services research, outcomes research, biostatistics, or related field Minimum 10 years of experience in real-world evidence, outcomes research, or epidemiology within the pharmaceutical or biotech industry Preferred Proven track record of leading RWE teams and delivering high-quality evidence generation programs Deep expertise in real-world data sources (claims, EHR, registries) and advanced analytic methods for observational studies Strong understanding of cardiometabolic diseases and their treatment landscape Demonstrated success in establishing and managing external research partnerships Experience supporting regulatory submissions with RWE (FDA, EMA) Excellent scientific writing and communication skills with multiple peer-reviewed publications Strong leadership, collaboration, and influence skills across matrixed organizations Experience with novel data sources including wearables, patient-generated data, and digital health platforms Knowledge of health economics and value demonstration methodologies (HEOR, budget impact, cost-effectiveness) Familiarity with FDA guidance on RWE for regulatory decision-making Experience in cardiometabolic therapeutic categories including incretins, amylins, insulins, and lipid-lowering medications Track record of identifying and advancing NILEX opportunities through RWE Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form ( https://careers.lilly.com/us/en/workplace-accommodation ) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response. Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status. Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ Allies), Veterans Leadership Network (VLN), Women’s Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Learn more about all of our groups. Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is $243,000 - $356,400 Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees. WeAreLilly

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